Anticonvulsant effects of Lippia citriodora (Verbenaceae) leaves ethanolic extract in mice: Role of gabaergic system

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anticonvulsant effects of lippia citriodora (verbenaceae) leaves ethanolic extract in mice: role of gabaergic system

background: lippia citriodora kunth is one of the iranian traditional medicines for the treatment of convulsive disorders. the goal of this study is to investigate the anticonvulsant activity of the plant’s leave ethanolic extract against electro‑ and chemoconvulsant‑induced seizures in mice. methods: the anticonvulsant activity of the extract (200, 400, 800 mg/kg, per os, p.o.) was investigate...

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Teratogenic effect of Lippia citriodora leaves aqueous extract in mice

OBJECTIVE Safety of Lippia citriodora, as a herbal remedy, in pregnancy has not yet been evaluated. This study aimed to identify the effect of L. citriodora aqueous extract on pregnancy outcome in mice. MATERIALS AND METHODS Timed-pregnant mice received doses of 0.5 g/kg/day L. citriodora aqueous extract or the vehicle control during organogenesis, intraperitoneally. Maternal body weights wer...

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Teratogenic effect of Lippia citriodora leaves aqueous extract in mice

Objective: Safety of Lippia citriodora, as a herbal remedy, in pregnancy has not yet been evaluated. This study aimed to identify the effect of L. citriodora aqueous extract on pregnancy outcome in mice. Materials and Methods: Timed-pregnant mice received doses of 0.5 g/kg/day L. citriodora aqueous extract or the vehicle control during organogenesis, intraperitoneally. Maternal body weights wer...

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Anti-anxiety and hypnotic effects of ethanolic and aqueous extracts of Lippia citriodora leaves and verbascoside in mice

Objectives: The extract of Lippia citriodora and its main component, verbascoside, are known for their hypnotic effects in traditional medicine. In this study, the anxiolytic and hypnotic effects of L. citriodora leave extracts and verbascoside were evaluated in mice. Materials and Methods: Animals were divided into 11 groups of six mice each. Group I received normal saline, Group II received ...

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teratogenic effect of lippia citriodora leaves aqueous extract in mice

objective: safety of lippia citriodora, as a herbal remedy, in pregnancy has not yet been evaluated. this study aimed to identify the effect of l. citriodora aqueous extract on pregnancy outcome in mice. materials and methods: timed-pregnant mice received doses of 0.5 g/kg/day l. citriodora aqueous extract or the vehicle control during organogenesis, intraperitoneally. maternal body weights wer...

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ژورنال

عنوان ژورنال: International Journal of Preventive Medicine

سال: 2016

ISSN: 2008-7802

DOI: 10.4103/2008-7802.187251